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Results 1 - 10 of 10
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EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.9ATP + goodpasture antigen enzyme is involved in autoimmune pathogenesis. Enzyme expression is up-regulated in the striated muscle of a Goodpasture patient and in other autoimmune conditions including cutaneous lupus erythematosus, pemphigoid, and lichen planus
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.9ATP + membrane type IV collagen GPBP serves as transporter of ceramide between the endoplasmic reticulum and the Golgi apparatus. The 91-kDa GPBP splicing variants regulates the levels of 77-kDa GPBP variant, i.e. GPBPDELTA26/CERT, in the extracellular compartment
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.9ATP + [Goodpasture antigen-binding protein] -
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.9ATP + [Goodpasture antigen-binding protein] autophosphorylation via the enzyme's serine/threonine kinase activity that specifically targets a motif in the NC1 domain of the alpha3 chain of type IV collagen, the Good pasture autoantigen, the enzyme is involved in autoimmune processes and disease
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.9ATP + [Goodpasture antigen-binding protein] the Goodpasture antigen-binding protein is an atypical protein kinase that phosphorylates the Goodpasture auto-antigen, the alpha3 chain of collagen IV
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.9ATP + [Goodpasture antigen-binding protein] the Goodpasture antigen-binding protein performs autophosphorylation
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.9ATP + [Goodpasture antigen-binding protein] the Goodpasture antigen-binding protein performs phosphorylation of collagen IV
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.9more disruption of the nonvesicular ceramide transport is detrimental to normal embryonic development of somites and brain because of increased apoptosis mediated by the CERT function of GBPB, but not GBPBDELT26, overview
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.9more Goodpasture antigen-binding protein binds to human serum amyloid P component specifically in its physiological conformations, i.e. pentamers and decamers. Collagen IV binds to serum amyloid P and to Goodpasture antigen-binding protein, the latter also binds laminin, binding studies and kinetics, overview
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.9more GPBP-1 targets the GPBP-interacting protein of 130 kDa, GIP130, which binds to myosin and promotes its myofibrillar assembly
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