EC Number   |
Natural Substrates |
|---|
   2.7.11.14 | ATP + a protein |
- |
| 2.7.11.14 | ATP + arrestin |
phosphorylation of arrestin in the presence of Ca2+, occurs only after photoactivation in vivo, dual role of RK in the inactivation of the squid visual system |
| 2.7.11.14 | ATP + arrestin |
the enzyme interacts with the squid visual arrestin, arrestin binding to photoactivated rhodopsin is a key mechanism of desensitization, overview |
| 2.7.11.14 | ATP + cone opsin |
light-dependent phosphorylation |
| 2.7.11.14 | ATP + M opsin |
M opsin binds to cone arrestin during cone phototransduction in the retina |
| 2.7.11.14 | ATP + opsin |
the enzyme is involved in the opsin deactivation process, GRK subtypes play a role in phosphorylating non-visual opsins in the particular extraretinal tissues |
| 2.7.11.14 | ATP + rhodopsin |
- |
| 2.7.11.14 | ATP + rhodopsin |
light-dependent deactivation of rhodopsin involves receptor phosphorylation that is mediated by the highly specific protein kinases rhodopsin kinase |
| 2.7.11.14 | ATP + rhodopsin |
enzyme is required for normal rhodopsin deactivation. Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase |
| 2.7.11.14 | ATP + rhodopsin |
null mutations in the rhodopsin kinase gene are a cause of Oguchi disease and extend the known genetic heterogeneity in congenital stationary night blindness |
