EC Number   |
Natural Substrates |
|---|
   2.7.1.59 | ATP + N-acetyl-D-glucosamine |
- |
| 2.7.1.59 | ATP + N-acetyl-D-glucosamine |
100% activity |
| 2.7.1.59 | ATP + N-acetyl-D-glucosamine |
first enzyme of N-acetyl-D-glucosamine salvage pathway |
| 2.7.1.59 | ATP + N-acetyl-D-glucosamine |
first reaction of inducible N-acetylglucosamine catabolic pathway, enables organism to grow on N-acetylglucosamine as sole carbon source |
| 2.7.1.59 | ATP + N-acetyl-D-glucosamine |
part of glycoprotein synthesis pathway |
| 2.7.1.59 | ATP + N-acetyl-D-glucosamine |
involved in UDP-N-acetylglucosamine formation |
| 2.7.1.59 | ATP + N-acetyl-D-glucosamine |
enzyme is important in cell wall murein recycling, 60% of the the murein of the side wall is degraded |
| 2.7.1.59 | more |
interaction of HXK1 with histone deacetylase SIR2 under filamentation inducing conditions |
| 2.7.1.59 | more |
the enzyme has a unique specificity for both amino sugars of the bacterial cell wall, N-acetylmuramic acid and N-acetylglucosamine, which are phosphorylated at the 6-hydroxyl group, see also EC 2.7.1.170, the kcat value is 1.5fold higher for the latter substrate. Neither the non-N-acetylated forms of the cell wall sugars, i.e., glucosamine and/or muramic acid, nor epimeric hexoses or 1,6-anhydro-MurNAc are substrates for the enzyme. Product identificsation by nonradioactive and radioactive TLC |
