EC Number |
Natural Substrates |
---|
2.7.1.105 | ATP + beta-D-fructose 6-phosphate |
- |
2.7.1.105 | ATP + beta-D-fructose 6-phosphate |
the inducible enzyme is an important regulator of glycolysis that may be responsible for sustaining the high glycolytic flux of rapidly proliferating leukemia cells |
2.7.1.105 | ATP + beta-D-fructose 6-phosphate |
enzyme plays an indirect yet key role in the regulation of glucose metabolism |
2.7.1.105 | ATP + beta-D-fructose 6-phosphate |
responsible for regulation of fructose 2,6-bisphosphate-concentration |
2.7.1.105 | ATP + beta-D-fructose 6-phosphate |
enzyme plays an important role in the regulation of hepatic carbohydrate metabolism |
2.7.1.105 | ATP + beta-D-fructose 6-phosphate |
carbon-partitioning in Arabidopsis is regulated by fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase |
2.7.1.105 | ATP + beta-D-fructose 6-phosphate |
PFKFB3 plays a crucial role in the progression of cancerous cells by enabling their glycolytic pathways even under severe hypoxic conditions |
2.7.1.105 | ATP + beta-D-fructose 6-phosphate |
PFKFB3 is a potent stimulator of glycolysis, up-regulated by inflammatory and hypoxic stimuli |
2.7.1.105 | more |
Cys-295 is involved in allosteric regulation |
2.7.1.105 | more |
evolution of the bifunctional enzyme |