EC Number |
Natural Substrates |
---|
2.6.1.66 | 3-methyl-2-oxobutanoate + L-glutamate |
the transamination of ketoisovalerate (KIV) to valine is carried out mainly by the transaminase B enzyme, with the transaminase C enzyme playing a minor role |
2.6.1.66 | L-alanine + 3-methyl-2-oxobutanoate |
mutations in the gene encoding this enzyme are silent unless they are combined with mutations involved in isoleucine-valine biosynthesis |
2.6.1.66 | L-alanine + 3-methyl-2-oxobutanoate |
probably involved in alanine biosynthesis, transaminase C is found at reduced levels upon starvation for any one of several amino acids |
2.6.1.66 | L-alanine + 3-methyl-2-oxobutanoate |
this enzyme deficiency results in conditional isoleucine auxotrophy in the presence of alanine |