EC Number   |
Natural Substrates |
|---|
    2.6.1.1 | L-aspartate + 2-oxoglutarate |
- |
| 2.6.1.1 | L-aspartate + 2-oxoglutarate |
key enzyme in assimilation of C and N compounds |
| 2.6.1.1 | L-aspartate + 2-oxoglutarate |
role in energy metabolism of diving animals |
| 2.6.1.1 | L-aspartate + 2-oxoglutarate |
enzyme plays the most important role in amino acid metabolism |
| 2.6.1.1 | L-aspartate + 2-oxoglutarate |
enzyme plays a central role in nitrogen metabolism of cells |
| 2.6.1.1 | L-aspartate + 2-oxoglutarate |
enzyme plays an important role in numerous metabolic processes |
| 2.6.1.1 | L-aspartate + 2-oxoglutarate |
anti-enzyme antibodies selectively inhibit the uptake of oleate in 3T3-L1 adipocytes by 31-55%, but only poorly in fibroblasts, the antibodies have no effect on uptake of 2-deoxyglucose and octanoate |
| 2.6.1.1 | L-aspartate + 2-oxoglutarate |
function in C4 acid pathway |
| 2.6.1.1 | L-aspartate + 2-oxoglutarate |
hyperprolinemia type II is an autosomal recessive disorder caused by severe deficiency of enzyme DELTA1-pyrroline-5-carboxylic acid dehydrogenase leading to tissue accumulation of proline. Proline has direct inhibitory effect on aspartate transaminase activity of different brain regions leading to lesser synthesis of glutamate thereby causing neurological dysfunctions |
