EC Number   |
Natural Substrates |
|---|
    2.5.1.31 | (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate |
- |
| 2.5.1.31 | (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate |
catalyzes the cis-prenyl chain elongation onto trans,trans-farnesyl diphosphate (FPP) to produce undecaprenyl diphosphate (UPP). The product undecaprenyl diphosphate is indispensable for the biosynthesis of bacterial cell walls |
| 2.5.1.31 | (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate |
catalyzes the condensation of eight molecules of isopentenyl pyrophosphate (IPP) with farnesyl diphosphate (FPP) to generate C55 undecaprenyl diphosphate. With a variety of different ratios of enzyme to substrate and FPP to IPP in the presence or absence of Triton, different product distributions are found |
| 2.5.1.31 | (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate |
catalyzes the sequential condensation of eight molecules of isopentenyl diphosphate (IPP) in the cis-configuration into farnesyl diphosphate (FPP) to produce undecaprenyl diphosphate (UPP), which is indispensable for the biosynthesis of the bacterial cell wall |
| 2.5.1.31 | (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate |
UPPS catalyzes eight consecutive condensation steps of IPP with FPP to form C55 final product |
| 2.5.1.31 | (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate |
the enzyme is responsible for the biogenesis of undecaprenyl phosphate, an indispensable glycosyl carrier lipid in bacterial cell wall biosynthesis |
| 2.5.1.31 | farnesyl diphosphate + isopentenyl diphosphate |
consecutive condensation of 8 molecules of isopentenyl diphosphate with farnesyl diphosphate to form the lipid carrier undecaprenyl diphosphate to mediate bacterial peptidoglycan synthesis |
| 2.5.1.31 | farnesyl diphosphate + isopentenyl diphosphate |
consecutive condensation of 8 molecules of isopentenyl diphosphate with farnesyl diphosphate to form the lipid carrier undecaprenyl diphosphate to mediate bacterial peptidoglycan synthesis, the final product has C55 chain length |
| 2.5.1.31 | farnesyl diphosphate + isopentenyl diphosphate |
consecutive condensation of 8 molecules of isopentenyl diphosphate with farnesyl diphosphate to form the lipid carrier undecaprenyl diphosphate to mediate bacterial peptidoglycan synthesis, the final product has C55-C60 chain length, molecular 3D-structural modeling of the reaction product |
| 2.5.1.31 | farnesyl diphosphate + isopentenyl diphosphate |
sequential condensation of 8 molecules of isopentenyl diphosphate in the cis-configuration into farnesyl diphosphate to produce undecaprenyl diphosphate, indispensable for the biosynthesis of bacterial cell wall |
