EC Number |
Natural Substrates |
---|
2.3.1.76 | acyl-CoA + retinol |
- |
2.3.1.76 | all-trans retinol + palmitoyl-CoA |
- |
2.3.1.76 | more |
the multifunctional O-acyltransferase likely plays an important role in lipid metabolism in human skin |
2.3.1.76 | more |
ARAT may complement LRAT, EC 2.3.1.135, to provide additional retinyl-ester synthase activity under conditions of high all-trans-retinol |
2.3.1.76 | more |
ARAT plays a role in retinol metabolism in tissues with low levels of cytosolic retinol binding protein or when cellular retinol concentrations are relatively high, thereby protecting cells from toxicity resulting from excess unesterified retinol |
2.3.1.76 | more |
cells and tissues from DGAT1-deficient mice exhibit reduced ARAT activity, and the mice have increased levels of unesterified retinol in their livers on a high-retinol diet |
2.3.1.76 | more |
the multifunctional enzyme plays an important role in lipid metabolism in human skin |
2.3.1.76 | palmitoyl-CoA + 11-cis-retinol |
- |
2.3.1.76 | palmitoyl-CoA + 11-cis-retinol |
esterification of 11-cis-retinol is four times greater than esterification of all-trans-retinol in Muller cells |
2.3.1.76 | palmitoyl-CoA + all-trans-retinol |
- |