EC Number |
Natural Substrates |
---|
2.1.2.8 | 5,10-methylenetetrahydrofolate + H2O + dCMP |
- |
2.1.2.8 | 5,10-methylenetetrahydrofolate + H2O + deoxycytidylate |
- |
2.1.2.8 | 5,10-methylenetetrahydrofolate + H2O + deoxycytidylate |
dCTP depresses the synthesis of 5-hydroxymethyldeoxycytidylate |
2.1.2.8 | 5,10-methylenetetrahydrofolate + H2O + deoxycytidylate |
the hydroxymethylation is catalyzed by dCMP hydroxymethylase, which transfers a methylene group from methylenetetrahydrofolate to C5 of dCMP and then uses a water molecule to hydrate the methylene group to form hydroxymethyl-dCMP, one precursor for phage DNA replication |
2.1.2.8 | more |
enzyme is part of the dNTP synthetase complex |
2.1.2.8 | more |
enzyme functions in vivo as a component of a multienzyme complex called dNTP synthetase |
2.1.2.8 | more |
enzyme is part of a complex efficiently channeling DNA precursors to the replication apparatus |
2.1.2.8 | more |
biosynthesis of enzyme de novo after infection |
2.1.2.8 | more |
enzyme is part of a complex catalyzing DNA precursor biosynthesis |
2.1.2.8 | more |
direct interaction between NDP kinase and dCMP hydroxymethylase |