EC Number |
Natural Substrates |
---|
2.1.1.9 | more |
role in detoxification of hydrogen sulfide that is generated by the colonic flora |
2.1.1.9 | more |
detoxification of xenobiotic thiols |
2.1.1.9 | more |
the enzyme may be involved in the detoxification of sulfur compounds produced by the degradation of glucosinolates to release them as volatile compounds. The volatile sulfur compounds, including CH3SH and CH3SCN and methyl halides, are believed to act as insecticidal or anti-pathogenic agents. Therefore, it is speculated that the enzyme plays a role in controlling the levels of anions that can inhibit metabolic enzymes in the leaves and also to protect them from damage caused by insects or pathogens |
2.1.1.9 | S-adenosyl-L-methionine + a thiol |
enzyme is not essential as methyl donor or as sulfur transport form, enzyme is involved in regulation of the free Met pool and the S-adenosyl-L-methionine level, SMM cycle, overview |
2.1.1.9 | thiocyanate + S-adenosyl-L-methionine |
AtHOL1 is involved in glucosinolate metabolism and defense against phytopathogens. CH3Cl synthesized by AtHOL1 could be considered a byproduct of NCS- metabolism |