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Results 1 - 9 of 9

EC Number	Natural Substrates	Commentary (Nat. Sub.)
2.1.1.57	more	maximum 2'O-MTase activity requires the cap and at least 6 nucleotides
2.1.1.57	more	the enzyme shows highest activity towards 7Me-GpppA-Cn where n equals at least four, and does not methylate GpppAC5 or pppAC5
2.1.1.57	S-adenosyl-L-methionine + 7Me-GpppA-C5	-
2.1.1.57	S-adenosyl-L-methionine + 7Me-GpppA-C5	exclusive methylation at the 2'O position
2.1.1.57	S-adenosyl-L-methionine + 7Me-GpppA-Cn	exclusive methylation at the 2'O position
2.1.1.57	S-adenosyl-L-methionine + a 5'-(N7-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA]	-
2.1.1.57	S-adenosyl-L-methionine + GpppA-Cn	exclusive methylation at the 2'O position
2.1.1.57	S-adenosyl-L-methionine + m7G(5')pppR-RNA	RNA-polymerase holoenzyme has methyltransferase activity: the same protein acts as methyltransferase and poly(A)-polymerase stimulatory factor VP39
2.1.1.57	S-adenosyl-L-methionine + m7G(5')pppR-RNA	final step in formation of 7-methylguanosine(5')pppNm-cap structure of viral RNA

Results 1 - 9 of 9

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Release 2023.1 (January 2023)