EC Number |
Natural Substrates |
---|
2.1.1.207 | S-adenosyl-L-methionine + 5-carboxymethylaminomethyluridine34 in tRNA |
TrmL catalyzes the methyl transfer from SAM to the 2'-OH of the wobble nucleotide in tRNALeu cmnm5UmAA, which decodes codons UUA and UUG in the Phe/Leu mixed box, and tRNALeu CmAA, which reads the UUG codon included in the Leu family box |
2.1.1.207 | S-adenosyl-L-methionine + 5-carboxymethylaminomethyluridine34 in tRNALeu |
- |
2.1.1.207 | S-adenosyl-L-methionine + 5-carboxymethylaminomethyluridine34 in tRNALeu |
the enzyme methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNALeu(CmAA) and tRNALeu(cmnm5UmAA) |
2.1.1.207 | S-adenosyl-L-methionine + cytidine34 in tRNA |
- |
2.1.1.207 | S-adenosyl-L-methionine + cytidine34 in tRNA |
the enzyme methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNALeu(CmAA) and tRNALeu(cmnm5UmAA) |
2.1.1.207 | S-adenosyl-L-methionine + cytidine34 in tRNALeuCAA |
- |
2.1.1.207 | S-adenosyl-L-methionine + cytidine34 in tRNALeuUAA |
- |