EC Number   |
Natural Substrates |
|---|
   1.3.99.5 | 5alpha-dihydrotestosterone + NADP+ |
5alpha-reductase converts testosterone to 5alpha-dihydrotestosterone |
| 1.3.99.5 | 5alpha-dihydrotestosterone + NADP+ |
the enzyme performs conversion of testosterone to 5alpha-dihydrotestosterone |
| 1.3.99.5 | 5alpha-pregn-3,20-dione + NADP+ |
5alpha-reductase also can act on progesterone, which is metabolized to an intermediate product that is then converted to allopregnanolone |
| 1.3.99.5 | deoxycorticosterone + reduced acceptor |
- |
| 1.3.99.5 | dihydrotestosterone + NADP+ |
the enzyme performs conversion of testosterone to dihydrotestosterone |
| 1.3.99.5 | dihydrotestosterone + NADP+ |
the isoenzyme efficiently catalyzes the in vitro transformation of testosterone into dihydrotestosterone |
| 1.3.99.5 | more |
neonatal testicular androgens, e.g. testosterone, irreversibly program several hepatic enzyme activities in the rat including 5alpha-reductase, tissue-specific physiological regulation of isozymes |
| 1.3.99.5 | more |
the enzyme produces precursors for the biosynthesis of allopregnenolone and tetrahydrodeoxycorticosterone, physiological role of the isozymes in the brain, overview |
| 1.3.99.5 | progesterone + reduced acceptor |
- |
| 1.3.99.5 | testosterone + reduced acceptor |
- |
