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EC Number
Natural Substrates
Commentary (Nat. Sub.)
1.3.1.48
11alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+
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1.3.1.48
15-ketoprostaglandin E + NAD(P)H
second step in metabolism of E- and Falpha-type prostaglandins
1.3.1.48
15-oxoprostaglandin F1alpha + NAD(P)H
second step in metabolism of E- and Falpha-type prostaglandins
1.3.1.48
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essential enzyme for eicosanoid inactivation
1.3.1.48
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bifunctional enzyme capable of inactivating leukotriene B4 and 15-oxo-prostaglandins, enzyme plays a role in growth suppressive functions in lung cancer
1.3.1.48
prostaglandin E2 + NADP+
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