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Results 1 - 6 of 6

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.14.20.13	(6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2	alkaloid metabolism, scopolamine is formed by oxidative transformation of hyoscyamine in several solanaceous species
1.14.20.13	(6S)-6beta-hydroxyhyoscyamine + 2-oxoglutarate + O2	-
1.14.20.13	(6S)-6beta-hydroxyhyoscyamine + 2-oxoglutarate + O2	via 6,7-dehydrohyoscyamine or not, two possible pathways for the epoxidation in the biosynthesis of scopolamine, overview
1.14.20.13	(6S)-hydroxyhyoscyamine + 2-oxoglutarate + O2	-
1.14.20.13	6,7-dehydrohyoscyamine + 2-oxoglutarate + O2	-
1.14.20.13	more	hyoscyamine 6beta-hydroxylase, a 2-oxoglutarate-dependent dioxygenase, converts L-hyoscyamine to its 6,7-epoxy derivative, scopolamine, in two sequential steps, the enzyme also catalyzes the reaaction of EC 1.14.11.11. 6,7-Dehydrohyoscyamine, a potential precursor for the last step of epoxidation, is an obligatory intermediate in the biosynthesis of scopolamine

Results 1 - 6 of 6

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Release 2023.1 (January 2023)