EC Number   |
Natural Substrates |
|---|
   1.14.14.3 | an aldehyde + FMNH2 + O2 |
- |
| 1.14.14.3 | beetle luciferin + FMNH2 + O2 |
- |
| 1.14.14.3 | coelenterazine + FMNH2 + O2 |
an imidazolopyrazine derivative |
| 1.14.14.3 | decanal + FMNH + O2 |
- |
| 1.14.14.3 | fatty aldehyde + FMNH2 + O2 |
- |
| 1.14.14.3 | luciferin + O2 + ATP |
- |
| 1.14.14.3 | more |
complex formation in a 1:1 molar ratio between monomeric, but not dimeric, NADPH:FMN oxidoreductase FRP and luciferase for direct transfer of cofactor FMNH2 |
| 1.14.14.3 | more |
luminescence pathway, overview |
| 1.14.14.3 | more |
the decay rate of the enzyme is determined by residue Glu175 of the central region of the LuxA subunit, distinction between slow and fast decay luciferases is primarily due to differences in aldehyde affinity and in the decomposition of the luciferase-flavin-oxygen intermediate |
| 1.14.14.3 | more |
the enzyme plays a role in protection of cells against oxidative stress |
