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Results 1 - 6 of 6

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.14.14.176	more	cDNAs encoding taxa-4(5),11(12)-diene synthase and CYP725A4 are introduced in Nicotiana sylvestris for specific expression in trichome cells. The co-expression does not lead to the production of the expected 5-hydroxytaxa-4(20),11(12)-diene. Instead, taxa-4(5),11(12)-diene is quantitatively converted to a novel taxane
1.14.14.176	taxa-4(20)-11(12)-diene + AH2 + O2	-
1.14.14.176	taxa-4(5),11(12)-diene + [reduced NADPH-hemoprotein reductase] + O2	hydroxylation of the C-5alpha is the first of the oxidations resulting in taxol
1.14.14.176	taxa-4,11-diene + [reduced NADPH-hemoprotein reductase] + O2	-
1.14.14.176	taxa-4,11-diene + [reduced NADPH-hemoprotein reductase] + O2	reaction is completely dependent on NADPH, enzyme catalyzes the first oxygenating step in taxol biosynthesis pathway
1.14.14.176	taxadiene + [reduced NADPH-hemoprotein reductase] + O2	-

Results 1 - 6 of 6

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Release 2023.1 (January 2023)