EC Number |
Natural Substrates |
---|
1.14.13.20 | 2,4-dichlorophenol + NADPH + H+ + O2 |
- |
1.14.13.20 | 2,4-dichlorophenol + NADPH + H+ + O2 |
best substrate |
1.14.13.20 | 2,4-dichlorophenol + NADPH + O2 |
- |
1.14.13.20 | 4-chloro-2-methylphenol + NADPH + O2 |
- |
1.14.13.20 | 4-chlorophenol + NADPH + O2 |
- |
1.14.13.20 | more |
the enzyme catabolizes 2,4-dichlorophenoxyacetate and 4-chloro-2-methylphenoxyacetate, using tfd functions carried on plasmid pJP4, tfdA cleaves the ether bonds of these herbicides to produce 2,4-dichlorophenol and 4-chloro-2-methylphenol, respectively, these intermediates can be degraded by two chlorophenol hydroxylases encoded by the tfdBI and tfdBII genes to produce the respective chlorocatechols, degradation pathway, a balance between chlorophenol-producing and chlorophenol-consuming reactions is necessary for growth on these compounds, overview |