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Results 1 - 10 of 23

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.14.11.69	a [histone H3]-N6,N6,N6-trimethyl-L-lysine36 + 2-oxoglutarate + O2	-
1.14.11.69	dimethyl-histone 3 L-lysine 36 + 2-oxoglutarate + O2	enzyme Rph1 is specific for di- and trimethyl-histone 3 L-lysine36
1.14.11.69	histone H3 N6,N6,N6-trimethyl-L-lysine36 + 2-oxoglutarate + O2	-
1.14.11.69	histone H3 N6,N6-dimethyl-L-lysine36 + 2-oxoglutarate + O2	-
1.14.11.69	histone H3 N6-methyl-L-lysine36 + 2-oxoglutarate + O2	-
1.14.11.69	histone H3-N6,N6,N6-trimethyl-L-lysine36 + 2-oxoglutarate + O2	-
1.14.11.69	histone H3-N6,N6,N6-trimethyl-L-lysine36 + 2-oxoglutarate + O2	KDM4A demethylates H3K36me3, a modification enriched in the 3' end of active genes
1.14.11.69	histone H3-N6,N6-dimethyl-L-lysine36 + 2-oxoglutarate + O2	-
1.14.11.69	more	general function of histone demethylase for histone 3 L-lysine 36 is to promote transcription elongation by antagonizing repressive L-lysine 36 methylation by Set2 methyltransferase
1.14.11.69	more	HP1a and dKDM4A interact with each other and loss of HP1a leads to an increased level of histone H3K36me3

Results 1 - 10 of 23

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Release 2023.1 (January 2023)