EC Number   |
Natural Substrates |
|---|
   1.14.11.16 | more |
overexpression may be associated with malignant transformation |
| 1.14.11.16 | more |
the enzyme hydroxylates epidermal growth factor-like domains in transformation-associated proteins |
| 1.14.11.16 | peptide L-asparagine + 2-oxoglutarate + O2 |
enzyme catalyzes the erythro-beta-hydroxylation of asparaginyl and aspartyl residues to form the 2S, 3R-product, possible role in the Notch signalling pathway |
| 1.14.11.16 | peptide L-asparagine + 2-oxoglutarate + O2 |
hydroxylation of Asn803 in hypoxia-inducible transcription factor, converted protein is incapable in interacting with the transcripitonal coactivator p300 |
| 1.14.11.16 | peptide L-aspartate + 2-oxoglutarate + O2 |
- |
| 1.14.11.16 | peptide L-aspartate + 2-oxoglutarate + O2 |
hydroxylates epidermal growth factor-like domains in transformation-associated proteins |
| 1.14.11.16 | peptide-L-aspartate + 2-oxoglutarate + O2 |
the enzyme catalyses hydroxylation of asparaginyl- and aspartyl-residues in epidermal growth factor-like domains |
| 1.14.11.16 | peptide-L-aspartate + 2-oxoglutarate + O2 |
the enzyme catalyzes the post-translational hydroxylation of Asp and Asn residues in epidermal growth factor-like domains |
