EC Number   |
Natural Substrates |
|---|
    1.1.1.363 | 6-phospho-D-gluconate + NAD+ |
- |
| 1.1.1.363 | 6-phospho-D-gluconate + NADP+ |
the enzyme generates NADPH, an essential cofactor for several biosynthetic pathways and antioxidant enzymes |
| 1.1.1.363 | D-glucose 6-phosphate + NAD+ |
- |
| 1.1.1.363 | D-glucose 6-phosphate + NADP+ |
- |
| 1.1.1.363 | more |
the reaction catalyzed by PputG6PDH-1 yields around 1/3 mol of NADPH and 2/3 mol of NADH per mol of oxidized glucose 6-phosphate, calculation of in vivo relative production of NADH and NADPH during the oxidation of glucose-6-phosphate. The reaction catalyzes by the 6-phosphogluconate dehydrogenase is active during growth on glucose, and it produces NADPH and NADH. In comparison, for the enzyme of Escherichia coli EcG6PDH, the relative production of NADH over NADPH is 1000times lower than for PputG6PDH-1 |
