EC Number   |
Natural Substrates |
|---|
   1.1.1.30 | (R)-3-hydroxybutanoate + NAD+ |
- |
| 1.1.1.30 | (R)-3-hydroxybutanoate + NADH + H+ |
the enzyme is involved in poly(3-hydroxybutyrate) biosynthesis together with acetoacetyl-CoA thiolase and PHB synthase, pathway overview, intracellular concentrations of key metabolites, i.e. CoA, acetyl-CoA, 3HB-CoA, NAD+/NADH, determine whether a cell accumulates or degrades PHB |
| 1.1.1.30 | (R)-3-hydroxybutyrate + NAD+ |
during hibernation, the enzyme is responsible for bioconvertion of high amounts of ketone bodies, i.e. acetoacetate and (R)-3-hydroxybutyrate, in the liver for usage as energetic fuel |
| 1.1.1.30 | (R)-3-hydroxybutyrate + NAD+ |
strain SA1 can degrade poly((R)-3-hydroxybutyrate), i.e. PHB |
| 1.1.1.30 | acetoacetate + NADH + H+ |
- |
| 1.1.1.30 | more |
enzyme activity is differently regulated in liver and brain at euthermic, prehibernating,and hibernating state |
| 1.1.1.30 | more |
a ketone body converting enzyme in mitochondria in liver jerboa, enzyme expression, activity and metabolism at different physiological states, overview |
