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EC Number
Natural Substrates
Commentary (Nat. Sub.)
1.1.1.179
D-xylose + NADP+
-
1.1.1.179
D-xylose + NADP+
best substrate
1.1.1.179
D-xylose + NADP+
enzyme has dehydrogenase and reductase activities, enzyme is identical to dihydrodiol dehydrogenase
1.1.1.179
D-xylose + NADP+
initial step in xylose degradation
1.1.1.179
L-arabinose + NADP+
44% of the activity with D-xylose
1.1.1.179
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D-xylose dehydrogenase catalyzes the NADP+-linked oxidation of dihydrodiols of aromatic hydrocarbons to their corresponding catechols and is regarded as a toxication enzyme in the metabolism of carcinogenic polycyclic aromatic hydrocarbons because oxidation by the enzyme yields reactive and redox-active ortho-quinones and reactive oxygen species, broad substrate specificity indicates additional roles of the enzyme in the metabolism of endogenous and xenobiotic carbonyl compounds and the prevention of the development of glycation
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