EC Number |
Natural Substrates |
---|
1.1.1.153 | 1'-oxo-2'-D-hydroxypropyl-tetrahydropterin + NADP+ |
- |
1.1.1.153 | 1'-oxo-2'-D-hydroxypropyl-tetrahydropterin + NADPH |
- |
1.1.1.153 | 1'-oxo-2'-hydroxypropyl-tetrahydropterin + NADPH + H+ |
- |
1.1.1.153 | 1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+ |
- |
1.1.1.153 | 1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADPH |
- |
1.1.1.153 | 6-(S)-lactoyl-7,8-dihydropterin + NADPH |
- |
1.1.1.153 | 6-(S)-lactoyl-7,8-dihydropterin + NADPH |
equilibrium lies much in favor of dihydrobiopterin formation |
1.1.1.153 | 6-(S)-lactoyl-7,8-dihydropterin + NADPH |
terminal step in the biosynthetic pathway for tetrahydrobiopterin |
1.1.1.153 | 6-(S)-lactoyl-7,8-dihydropterin + NADPH |
reverse reaction, L-erythro and L-threo-dihydroneopterin are also oxidized, the corresponding D-isomers are inactive |
1.1.1.153 | 6-(S)-lactoyl-7,8-dihydropterin + NADPH |
catalyzes the complete reduction of pyrovoyltetrahydropterin to tetrahydrobiopterin |