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Results 1 - 10 of 18

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.1.1.149	17alpha,20alpha-dihydroxypregn-4-en-3-one + NAD(P)+	inactive molecule form
1.1.1.149	17alpha-hydroxyprogesterone + NAD(P)H	-
1.1.1.149	17alpha-hydroxyprogesterone + NAD(P)H	NADPH is preferred to NADH in liver, while the kidney enzyme is specific for NADPH
1.1.1.149	17alpha-hydroxyprogesterone + NAD(P)H	progesterone catabolism
1.1.1.149	17alpha-hydroxyprogesterone + NAD(P)H	regulation of enzyme expression during pregnancy, the enzyme is required for prostaglandin F2alpha-dependent progesterone down-regulation before parturition, overview
1.1.1.149	17alpha-hydroxyprogesterone + NAD(P)H	the aldo-keto reductase, AKR1C23, also shows 20alpha-hydroxysteroid dehydrogenase activity in vivo, enzyme regulation in preovulatory follicles and corpora lutea, overview
1.1.1.149	17alpha-hydroxyprogesterone + NAD(P)H	the enzyme activity is highest in women with visceral obesity
1.1.1.149	5alpha-dihydroprogesterone + NADPH + H+	-
1.1.1.149	cortisol + NADH + H+	-
1.1.1.149	daunorubicin + NADPH + H+	inactivation of the anticancer drug

Results 1 - 10 of 18

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Release 2023.1 (January 2023)