EC Number   |
Natural Substrates   |
|---|
  3.5.4.25 | GTP + 3 H2O |
first committed step in the biosynthesis of riboflavin, overview |
  3.5.4.25 | GTP + 3 H2O |
- |
  3.5.4.25 | GTP + 4 H2O |
- |
  3.5.4.25 | GTP + H2O |
- |
  3.5.4.25 | GTP + H2O |
first committed step in the biosynthesis of riboflavin, overview |
  3.5.4.25 | GTP + H2O |
enzyme catalyzes the first step in the biosynthesis of riboflavin |
  3.5.4.25 | more |
RibA is the rate limiting enzyme in an industrial riboflavin producing strain |
  3.5.4.25 | more |
substitution of Met with His leads to a protein that catalyzes the production of both 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate and 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate with equal efficiency |
  3.5.4.25 | more |
enzyme may be involved in the biosynthesis of toxoflavin, which is produced from GTP in a series of steps that are likely initiated by GCH II |
  3.5.4.25 | more |
GTP cyclohydrolase II is a slow GTPase |