EC Number   |
Natural Substrates  |
|---|
   3.4.21.4 | DrmSP8-36 + H2O |
trypsin is the major endopeptidase regulating N-terminal truncated sex peptide DrmSP8-36 in hemolymph, the trypsin cleavage site R7-K8 is essential for release of the C-terminal fragment SP8-36 from sperm tail, the protein is cleaved more rapidly and completely in mated female hemolymph |
| 3.4.21.4 | enhanced green fluorescent protein-T1 + H2O |
enhanced green fluorescent protein-T1 is specifically cleaved into two major fragments by trypsin at the grafted cleavage site, approximately 20 and 8 kDa |
| 3.4.21.4 | enhanced green fluorescent protein-T2 + H2O |
enhanced green fluorescent protein-T2 is specifically cleaved into two major fragments by trypsin at the grafted cleavage site, approximately 18 and 10 kDa |
| 3.4.21.4 | Gelatin + H2O |
- |
| 3.4.21.4 | human cartilage collagen type II + H2O |
use of enzyme and its regulators as markers of prognosis and disease activity in rheumatoid arthritis |
| 3.4.21.4 | intestinal alkaline sphingomyelinase bound to mucosa + H2O |
cleavage at R440, first tryptic site upstream of signal anchor. Physiological role of enzyme in sphingomyelin digestion |
| 3.4.21.4 | more |
capable of agglutinating both bloodstream-form and procyclic trypanosomes as well as rabbit red blood cells |
| 3.4.21.4 | more |
trypsin treatment alters a number of characteristics of KATP channel pharmacology, this may be due to action at possibly more than one site but includes the functional cleavage of the sulfonylurea receptor from the KATP channel |
| 3.4.21.4 | more |
enzyme pancreatic isoforms cationic trypsin and anionic trypsin show activity on human proteinase-activated receptors PAR-1, PAR-2, PAR-3 comparable to that of bovine pancreatic trypsin. Mesotrypsin cannot activate or disable proteinase-activated receptors in human epithelial cells, but activates PAR-1 in human astrocytoma cells |
| 3.4.21.4 | more |
active 1918 pandemic flu viral neuraminidase is resistant to trypsin digestion |
