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Results 1 - 10 of 16 > >>
EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.20alkylated DNA + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.20alkylated DNA + H2O important role in preventing the mutagenic effects of deaminated purines and cyclic etheno adducts
Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.20alkylated DNA + H2O also removes 7-methylguanine
Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.20alkylated DNA + H2O smallest member of the helix-hairpin-helix HhH superfamily of DNA glycosylases
Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.20alkylated DNA + H2O double-stranded DNA is an effective substrate, enzyme is less efficient in excision of base damage from single-stranded regions transiently formed in DNA during transcription and replication
Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.20alkylated DNA + H2O cellular repair of alkylated DNA base modifications
Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.20alkylated DNA + H2O reaction of the enzyme with alkylated DNA leads to introduction of apurinic sites but no chain breaks
Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.20alkylated DNA + H2O nuclear transcription factor estrogen receptor alpha interacts with 3-methyladenine DNA glycosylase to modulate transcription and DNA repair, enzyme catalyzes removal of hypoxanthine from DNA, estrogen receptor alpha stabilizes the interaction of the enzyme with hypoxanthine containing DNAand increases the catalytic removal of the modified base
Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.20alkylated DNA + H2O primarily removes N3-methyladenine but also N3-methylguanine from DNA by glycosylic cleavage in the first step of the base excision repair
Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.20alkylated DNA + H2O constitutive pathway for repair of DNA damaged by simple alkylating agents such as methylmethanesulfonate and N-methyl-N'-nitro-N-nitrosoguanidine
Results 1 - 10 of 16 > >>