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EC Number
Natural Substrates
Commentary (Nat. Sub.)
2.7.4.9
ATP + dTMP
-
2.7.4.9
ATP + thymidine
-
2.7.4.9
ATP + TMP
-
2.7.4.9
L-dTMP + ATP
-
2.7.4.9
ATP + dTMP
involved in dTTP metabolism, essential for cell proliferation
2.7.4.9
ATP + TMP
involved in TTP metabolism
2.7.4.9
ATP + dTMP
involved in TTP metabolism, required for the activation of clinically relevant thymidine analogs such as anti-HIV and anti-cancer prodrugs
2.7.4.9
more
key enzyme in nucleotide synthesis
2.7.4.9
more
multifunctional enzyme which also phosphorylates pyrimidine nucleosides, pyrimidine nucleoside monophosphates, and several nucleoside analogues
2.7.4.9
ATP + dTMP
reaction in both the de novo and salvage pathways of dTTP synthesis
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