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EC Number
Natural Substrates
Commentary (Nat. Sub.)
ATP + dTMP
-
ATP + dTMP
reaction in both the de novo and salvage pathways of dTTP synthesis
ATP + dTMP
involved in dTTP metabolism, essential for cell proliferation
ATP + dTMP
involved in TTP metabolism, required for the activation of clinically relevant thymidine analogs such as anti-HIV and anti-cancer prodrugs
ATP + thymidine
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ATP + TMP
-
ATP + TMP
involved in TTP metabolism
dTMP + ATP
TMPK catalyzes the conversion of dTMP to dTDP, using ATP as its preferred phosphoryl donor. Part of the biosynthetic pathway for deoxythymidine triphosphate (dTTP).
L-dTMP + ATP
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more
key enzyme in nucleotide synthesis
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