EC Number |
Natural Substrates |
---|
3.4.22.38 | Protein + H2O |
remodeling of extracellular bone matrix, together with other collagenolytic and gelatinolytic enzymes |
3.4.22.38 | Protein + H2O |
involved in bone resorption, hydrolysis of proteinaceous bone matrix in the process of remodeling of the human skeleton |
3.4.22.38 | soluble calf-skin collagen + H2O |
- |
3.4.22.38 | tartrate resistant acid phosphatase + H2O |
- |
3.4.22.38 | tartrate-resistant acid phosphatase + H2O |
cathepsin K, colocalizes with tartrate-resistant acid phosphatase in osteoclast-resorptive compartments, supporting a role for cathepsin K in the extracellular processing of monomeric tartrate-resistant acid phosphatase in the resorption lacuna |
3.4.22.38 | tissue growth factor beta1 + H2O |
- |
3.4.22.38 | Type I collagen + H2O |
- |
3.4.22.38 | Type I collagen + H2O |
cleavage sites in type I collagen are telopeptides and multiple sites in triple helix |
3.4.22.38 | type II collagen + H2O |
cathepsin K cleaves the triple helix of type II collagen |
3.4.22.38 | type III collagen + H2O |
- |