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Results 11 - 16 of 16

EC Number	Natural Substrates	Commentary (Nat. Sub.)
3.2.2.20	alkylated DNA + H2O	constititively expressed
3.2.2.20	alkylated DNA + H2O	initiates the base excision repair pathway by removing damaged bases to create abasic apurinic/apyrimidinic sites
3.2.2.20	alkylated DNA + H2O	50% of DNA alkylation is repaired in the first 60 min after treatment with methyl methanesulfonate
3.2.2.20	alkylated DNA + H2O	highest activity by producing 3-methylguanine
3.2.2.20	more	AlkC is involved exclusively in the repair of alkylation damage
3.2.2.20	more	3-methyladenine DNA glycosylase recognizes and excises a broad range of purines damaged by alkylation and oxidative damage, including 3-methyladenine, 7-methylguanine, hypoxanthine, and 1,N6-ethenoadenine

Results 11 - 16 of 16

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Release 2023.1 (January 2023)