EC Number   |
Metals/Ions |
Reference |
|---|
   7.2.2.13 | Ba2+ |
activates |
710811 |
| 7.2.2.13 | Ca2+ |
activates |
710811 |
| 7.2.2.13 | Cd2+ |
a significant increase in enzyme activity is observed after exposure to Cd2+ in a concentration-dependent manner (about 3.5fold increase in activity at 7.5 mg/l, about 5.8fold increase in activity at 15 mg/l) |
752295 |
| 7.2.2.13 | Cr3+ |
causes oxidative stress in fish and leads to reduced enzyme activity in the brain, mechanism, overview. The level of ATP production in brain mitochondria may be an important criteria in the CrIII induced inhibition of Na+K+ATPase activity of fish brain, reduction of Na+K+ATPase activity is partially mediated by lipid peroxidation and deficient mitochondrial electron transport chain activity. Also direct interaction of CrIII ion with the -SH group of Na+K+ATPase enzyme might play a role |
711650 |
| 7.2.2.13 | Cs+ |
the Na,K pump is activated by the combined effect of Na+ on the cytoplasmic side and of K+ on the extracellular side of the membrane. K+ can be replaced by the following monovalent cations in the order of decreasing activation: K+, Rb+, NH4+, Cs+, Li, Na+ |
246967 |
| 7.2.2.13 | K+ |
- |
655251, 655269, 697452 |
| 7.2.2.13 | K+ |
activates |
735111 |
| 7.2.2.13 | K+ |
activation mechanism in simultaneous presence of Na+ and K+ |
246968 |
| 7.2.2.13 | K+ |
completely abolishes oubain binding to alpha1-beta1 isoenzymes. Residual oubain binding is still observed at high K+ concentrations for alpha2-beta1 and alpha3-beta1 complexes |
246960 |
| 7.2.2.13 | K+ |
half-activated by 2.0 mM |
246953 |
