EC Number   |
Metals/Ions |
Reference |
|---|
    6.1.1.2 | KCl |
optimal concentration: 50 mM |
85 |
| 6.1.1.2 | Mg2+ |
- |
672219, 673324, 674218, 675928, 676170, 676210, 676229, 676863, 692756 |
| 6.1.1.2 | Mg2+ |
Km: 1.5 mM |
85 |
| 6.1.1.2 | Mg2+ |
Mg2+-ATP interactions are coupled to interactions between ATP and active-site lysine side-chains |
675401 |
| 6.1.1.2 | Mg2+ |
required |
650171, 652900, 653740, 716055, 716156, 716370, 727987, 743913, 745352, 745868, 746452 |
| 6.1.1.2 | Mn2+ |
replacing Mg2+ with Mn2+ reduces the specificity for L-tryptophan, increasing the relative activation of L-tyrosine by about 3.5fold |
727987 |
| 6.1.1.2 | more |
no effects by Fe2+ and diphosphate |
672219 |
| 6.1.1.2 | Zn2+ |
- |
703734 |
| 6.1.1.2 | Zn2+ |
enhances activity |
702375 |
| 6.1.1.2 | Zn2+ |
required |
288 |
