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EC Number Metals/Ions Commentary Reference
Show all pathways known for 4.2.1.109Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.109more MtnB requires metal ions for catalysis, but it is unclear what kind of metal ions are bound to the MtnB purified from Escherichia coli cells. Considering that FucA/RibE/RhuA-related enzymes require the zinc ion for optimal catalysis under physiological conditions and that recombinant class II aldolase enzymes expressed in Escherichia coli cells are almost all of the Zn2+ form, purified MtnB might also be of the Zn2+ form 691391
Show all pathways known for 4.2.1.109Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.109Zn2+ near the zinc ion, the surface of the active site pocket is formed by several residues, including Cys97, Tyr198, Glu139, Lys142, and Asn166. Residues Cys97, Glu139, and Tyr198 form hydrogen bonds with the three water molecules that coordinate the zinc ion 730835
Show all pathways known for 4.2.1.109Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.109Zn2+ required by the enzyme protein 728588
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