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EC Number Metals/Ions Commentary Reference
Show all pathways known for 3.5.4.25Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.25Mg2+ - 675226
Show all pathways known for 3.5.4.25Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.25Mg2+ divalent cations 246730
Show all pathways known for 3.5.4.25Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.25Mg2+ Mg2+ dependent 209545, 246729
Show all pathways known for 3.5.4.25Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.25Mg2+ required 726585, 734013
Show all pathways known for 3.5.4.25Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.25Zn2+ contains 1 molar equivalent of zinc per mol of protein 685065
Show all pathways known for 3.5.4.25Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.25Zn2+ contains zinc 726585
Show all pathways known for 3.5.4.25Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.25Zn2+ contains Zn2+ 734013
Show all pathways known for 3.5.4.25Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.25Zn2+ content 1 molecule per monomer enzyme, enzyme requires a zinc ion which presumably activates a water molecule for excision of C-8 of GTP 696250
Show all pathways known for 3.5.4.25Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.25Zn2+ content of 1 molecule per enzyme monomer, enzyme requires a zinc ion which presumably activates a water molecule for excision of C-8 of GTP 696250
Show all pathways known for 3.5.4.25Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.25Zn2+ wild-type enzyme contains 0.71 mol Zn2+ per mol of subunit, while the content in the mutant enzymes is reduced to below 0.1 mol Zn2+ per mol of subunit, essential for activity, bound to the active site, required for ring opening and formate release with zinc acting as a Lewis acid, which activates the 2 water molecules involved in the sequential hydrolysis of 2 carbon-nitrogen bonds 655443
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