EC Number   |
Metals/Ions |
Reference |
|---|
    3.5.1.116 | Ca2+ |
slight increase of activity |
34479 |
| 3.5.1.116 | Fe2+ |
slight increase of activity |
34479 |
| 3.5.1.116 | Mg2+ |
slight increase of activity |
34479 |
| 3.5.1.116 | Mn2+ |
activates, maximal activity at 0.2 mM |
34479 |
| 3.5.1.116 | Mn2+ |
Mn2+ is required for maximum catalytic activity. The bimetal reaction center of the enzyme is located at the pocket enclosed by the catalytic domain, dimerization domain, and other structural elements from a different subunit, structure, overview |
734481 |
| 3.5.1.116 | Mn2+ |
substrate (S)-ureidoglycine is bound to the Mn2+ ion at the active site of homooctameric enzyme. The Mn2+ ion acts as a molecular anchor to bind (S)-ureidoglycine, and its binding mode dictates the enantioselectivity of the reaction |
734179 |
| 3.5.1.116 | Zn2+ |
activates |
34479 |
