EC Number |
Metals/Ions |
Reference |
---|
3.4.24.87 | Ba2+ |
- |
682898 |
3.4.24.87 | Ba2+ |
activates |
650710, 711560, 711561, 711579, 712899 |
3.4.24.87 | Ba2+ |
activates, metalloprotease |
650709 |
3.4.24.87 | Ba2+ |
barium ions stimulate ADAMTS13 activity in citrated plasma but not in citrate-free plasma, cleavage of von Willebrand factor by recombinant ADAMTS13 is activated up to 200fold by barium ions |
669524 |
3.4.24.87 | Ba2+ |
best activating metal ion |
650102, 650717 |
3.4.24.87 | Ba2+ |
complete proteolysis is observed at 37°C in the presence of BaCl2 while about 25% von Willebrand factor still binds to collagen when BaCl2 supplementation is omitted |
668076 |
3.4.24.87 | Ba2+ |
in the presence of 10 mM Ba2+, the activity is enhanced 1.1 to 1.4fold |
719761 |
3.4.24.87 | Ca2+ |
activates |
711561 |
3.4.24.87 | Ca2+ |
activating |
650717 |
3.4.24.87 | Ca2+ |
ADAMTS13 activity in the reaction buffer containing 0.9 mM Ca2+ without incubation is enhanced 2.7times compared to the value determined in the absence of Ca2+. The activity of ADAMTS13 in the presence of 10 mM Ca2+ is enhanced 3-5fold |
719761 |