EC Number   |
Metals/Ions |
Reference |
|---|
   3.4.24.26 | Ca2+ |
a calcium ion is also required for enzyme activity, and stabilizes its tertiary structure. Contact with the calcium ion is made by the carboxyl groups of Asp136, Glu172, Glu175, and Asp183, the carbonyl group of Leu185, and one water molecule |
733746 |
| 3.4.24.26 | Mn2+ |
inhibits activity at 10 mM |
664291 |
| 3.4.24.26 | more |
metalloprotease |
717465, 717954 |
| 3.4.24.26 | more |
metalloprotease, the enzynme contains the typical metalloendopeptidases consensus zinc-binding sequence HEXXH |
717673 |
| 3.4.24.26 | more |
Mg2+ and Ca2+ at 0.625 mM have no effect on the activity, Mn2+, Co2+, and Fe3+ at 0.625 mM partly inhibit the enzyme, Zn2+ and Cu2+ inhibit the enzyme completely |
665249 |
| 3.4.24.26 | Ni2+ |
inhibits activity at 10 mM |
664291 |
| 3.4.24.26 | Zinc |
contains 0.9 atom Zn per molecule |
31115 |
| 3.4.24.26 | Zinc |
contains 1 atom Zn per molecule |
31116 |
| 3.4.24.26 | Zinc |
contains zinc |
31114, 31115, 31116 |
| 3.4.24.26 | Zinc |
elastase is a zinc containing metalloprotease |
665160 |
