EC Number   |
Metals/Ions |
Reference |
|---|
   3.1.4.11 | (NH4)2SO4 |
high salt concentration, (NH4)2SO4, 2 M, dissociates the high molecular weight form yielding the low molecular form and increasing the specific activity |
285237 |
| 3.1.4.11 | Ca2+ |
- |
135144, 135145, 668701, 677866, 691473, 691984, 692141, 693253, 693258, 693734 |
| 3.1.4.11 | Ca2+ |
absolute requirement for both isoenzymes. Maximal activity with phosphatidylinositol at pH 5.5: 1 mM. Maximal activity with phosphatidylinositol 4,5-diphosphate at pH 7.0: 0.1 mM |
135136 |
| 3.1.4.11 | Ca2+ |
activated by, optimal concentration 1 mM |
285231 |
| 3.1.4.11 | Ca2+ |
activates |
135127, 135131, 751269 |
| 3.1.4.11 | Ca2+ |
activates PLCdelta1, EC50: 0.0057 mM, PLCdelta1 has a 100fold lower Ca2+ sensitivity than PLCzeta |
652515 |
| 3.1.4.11 | Ca2+ |
activates, maximal activity at 0.01 mM |
135118, 653195 |
| 3.1.4.11 | Ca2+ |
activates, the two recombinant enzymes synthesized from two potential initiation codons differ in their Ca2+ requirements |
652651 |
| 3.1.4.11 | Ca2+ |
activity of PLC-delta1 increases at a Ca2+ concentration between 0.001 and 0.03 mM |
652515 |
| 3.1.4.11 | Ca2+ |
all PLC isozymes require calcium for their activity, the PLCdelta-type is one of the most sensitive to calcium, suggesting that the activity of the PLCdelta-type may be regulated by calcium. PLCzeta is extremely sensitive to the calcium concentration |
716810 |
