EC Number   |
Metals/Ions |
Reference |
|---|
   3.1.21.7 | Ca2+ |
no catalytic function, supports binding to DNA |
678135 |
| 3.1.21.7 | Ca2+ |
protein binding, D43, E89, D110, and H214 have been identified as active site residues that are involved in metal coordination |
678294 |
| 3.1.21.7 | Co2+ |
supports oxanosine-containing DNA cleavage to a small extent |
666476 |
| 3.1.21.7 | Mg2+ |
- |
678135 |
| 3.1.21.7 | Mg2+ |
a divalent metal ion is required for the enzyme to cleave DNA, Mn2+ (1 mM) and Mg2+ (1 mM) are optimal |
750798 |
| 3.1.21.7 | Mg2+ |
activity is stimulated by the presence of Mg2+ or Mn2+ in the reaction buffer, with an optimum at 1 mM Mg2+ |
725322 |
| 3.1.21.7 | Mg2+ |
best activity at pH 8.5 and 2.5 mM Mg2+ |
752190 |
| 3.1.21.7 | Mg2+ |
contains one Mg2+ ion in the active site, which is required for activity |
694329 |
| 3.1.21.7 | Mg2+ |
DNA cleavage, D43, E89, D110, and H214 have been identified as active site residues that are involved in metal coordination |
678294 |
| 3.1.21.7 | Mg2+ |
highest cleavage activity for deoxyinosine-containg DNA at 2 mM |
288775 |
