EC Number   |
Metals/Ions |
Reference |
|---|
    2.7.7.1 | Ca2+ |
- |
642807, 642811 |
| 2.7.7.1 | Co2+ |
- |
642791, 642798, 642807, 642811 |
| 2.7.7.1 | Co2+ |
10 mM, the enzyme requires divalent cations for the activity. MgCl2 is the most effective additive. can replace Mg2+ with 51% of the activity compared to 10 mM Mg2+ |
745568 |
| 2.7.7.1 | Co2+ |
isoform NMNAT3 is predominantly activated by Co2+ ions (5 mM) |
723599 |
| 2.7.7.1 | Co2+ |
metal ion required. Order of decreasing effectiveness: Co2+, Ni2+, Mg2+, Zn2+, Mn2+, isoform yNMNAT-2 |
661539 |
| 2.7.7.1 | Co2+ |
metal ion required. Order of decreasing effectiveness: Ni2+, Zn2+, Co2+, Mg2+, Mn2+, isoform yNMNAT-1 |
661539 |
| 2.7.7.1 | Co2+ |
most effective, 0.5 mM giving the same extent of activation like 10 mM Mg2+ |
642801 |
| 2.7.7.1 | Co2+ |
Ni2+ supports enzyme activity most efficiently, followed by Co2+, Mg2+, and Mn2 |
761553 |
| 2.7.7.1 | Cu2+ |
- |
642801 |
| 2.7.7.1 | Cu2+ |
10 mM, the enzyme requires divalent cations for the activity. MgCl2 is the most effective additive. can replace Mg2+ with 28% of the activity compared to 10 mM Mg2+ |
745568 |
