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EC Number
Metals/Ions
Commentary
Reference
2.7.11.5
Mg2+
-
640610
2.7.11.5
Mg2+
2 mM used in assay conditions
738248
2.7.11.5
Mg2+
absolute requirement, isocitrate dehydrogenase phosphatase responds hyperbolically to Mg2+ ions
640602
2.7.11.5
Mg2+
activates
760671
2.7.11.5
Mg2+
required
721649
2.7.11.5
Mg2+
required, only one Mg2รพ is found in AceK, whereas two are present in ePKs
723346
2.7.11.5
Mn2+
activates. Mn2+ and Mg2+ do not compete for the same binding site. Mn2+ appears to bind to the regulatory domain of AceK, and its effect is transmitted to the active site of the enzyme by the conformational change that it induces
760671
2.7.11.5
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Mn2+ or Ca2+ cannot replace Mg2+
640602
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