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EC Number	Metals/Ions	Commentary	Reference
2.7.1.40	Ca2+	activation	641539
2.7.1.40	Ca2+	activation at low Mg2+ and low Ca2+-concentration	654470
2.7.1.40	Ca2+	divalent cation required, at 1 mM Ca2+ activation results in 14% of the activity with Mg2+	662143
2.7.1.40	Ca2+	divalent cation required, at 1 mM Ca2+ activation results in 3% of the activity with Mg2+	662143
2.7.1.40	Ca2+	divalent cation required, at 1 mM Ca2+ activation results in 7% of the activity with Mg2+	662143
2.7.1.40	Ca2+	not	641584, 641586, 641589
2.7.1.40	Cd2+	multiphasical activation, at pH below physiological value, inhibits at physiological pH	641533
2.7.1.40	Co2+	activates	760784
2.7.1.40	Co2+	activation	641556
2.7.1.40	Co2+	can replace Mg2+	641584

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Release 2023.1 (January 2023)