EC Number   |
Metals/Ions |
Reference |
|---|
   2.4.1.37 | Ca2+ |
0.1 mM, significant increase in activity, more significant acceleration at 10 mM |
674682 |
| 2.4.1.37 | Co2+ |
slight activation |
489130 |
| 2.4.1.37 | Hg |
structures of the mercury derivative of GTB and GTB C209A, mercury does not affect the conformation of active-site residues, the structure of GTB C209A demonstrates that the mercury coordinated by Cys209 is partially responsible for the disorder of the 16-amino-acid internal loop observed in the heavy-atom structure of GTB |
690230 |
| 2.4.1.37 | KCl |
lower activity compared to NaCl, best at 50 mM |
659358 |
| 2.4.1.37 | Mg2+ |
0.1 mM, significant increase in activity, more significant acceleration at 10 mM |
674682 |
| 2.4.1.37 | Mg2+ |
4fold lower activity compared to Mn2+ |
659358 |
| 2.4.1.37 | Mg2+ |
activates, GTB requires divalent metal ions for full activity |
703919 |
| 2.4.1.37 | Mg2+ |
activity depends on a bivalent cation |
719291 |
| 2.4.1.37 | Mn2+ |
- |
489114, 489115, 489122, 660551, 690409, 693025 |
| 2.4.1.37 | Mn2+ |
0.1 mM, significant increase in activity |
674682 |
