EC Number   |
Metals/Ions |
Reference |
|---|
    1.5.1.8 | Ca2+ |
0.5 mM Ca+ used in assay conditions |
724927 |
| 1.5.1.8 | Ca2+ |
1.6 mM, activates |
392367 |
| 1.5.1.8 | Ca2+ |
activates separated lysine-oxoglutarate reductase domain and this domain in bifunctional protein, Ca2+ may be the most important physiological modulator of enzyme activity, it possibly activates through the derepression of an inhibitory domain in vivo |
392369 |
| 1.5.1.8 | Ca2+ |
activates the LKR domain activity |
763097 |
| 1.5.1.8 | Ca2+ |
activates, lysine 2-oxoglutarate reductase activity is modulated by Ca2+, possible modulation of an inhibitory domain |
392367 |
| 1.5.1.8 | Mg2+ |
activates |
392367 |
| 1.5.1.8 | Mg2+ |
activates at millimolar concentrations |
392369 |
| 1.5.1.8 | Mg2+ |
activates the LKR domain activity |
763097 |
| 1.5.1.8 | Salt |
activated by high salt concentrations |
392367 |
| 1.5.1.8 | Salt |
e.g. NaCl or KCl, high salt concentrations activate bifunctional enzyme, but not separated lysine-oxoglutarate reductase domain, 15fold increase of enzyme activity when salt concentration is increased from 0 to 200 mM, effect is due to decreased water activity which could induce conformational modification in LOR domain of enzyme or activation may result from stabilizing effect of the dimeric form of enzyme |
392369 |
