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Results 1 - 6 of 6
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EC Number Metals/Ions Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65Fe2+ dependent on 746537
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65Fe2+ in presence of Fe2+ and 2-oxoglutarate, Fe2+ sits in the center of the c-PHF8 catalytic core, which consists of nine hydrophobic residues. Binding of 2-oxoglutarate to Fe2+ does not drastically change the conformation, however it causes the side chain of Y257 to turn towards the substrate binding channel, to be in a position to contact the methyl group of K9me2 711703
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65Fe2+ JMJ27 is a nuclear protein containing a zinc-finger motif and a catalytic JmjC domain with conserved Fe(II) and alpha-ketoglutarate binding sites 746085
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65Fe2+ required 744188, 753164
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65Fe2+ required for catalysis 744861, 745752, 745951
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65Ni2+ required 757427
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