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EC Number Metals/Ions Commentary Reference
Display the reaction diagram Show all sequences 1.13.12.23Fe2+ a non-heme iron enzyme, Fe2+ is required for enzyme activity. Replacement of Fe2+ with other monovalent or divalent metal ions (1 mM Cu+, Zn2+, Mg2+, or Mn2+) results in almost complete (95-98%) loss of enzymatic activity 742826
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