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EC Number
Metals/Ions
Commentary
Reference
Mg2+
cofactor
Mg2+
Mn2+ is more effective than Mg2+ in activation of dehydrosqualene formation; most effective in stimulation of squalene formation, half-maximal activity at 2.5 mM
Mg2+
Mn2+ is more effective than Mg2+ in activation of dehydrosqualene formation; required for squalene synthase reaction
Mg2+
Mn2+ is six times more effective in activation than Mg2+
Mg2+
no effect
Mg2+
required for squalene synthase reaction
Mg2+
required, best at 1,25 mM
Mg2+
required, best at 10 mM, inhibition above 35 mM
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