EC Number |
Localization |
GeneOntology No. |
Reference |
---|
3.5.1.26 | endoplasmic reticulum |
AGA maturation, activation cleavage of the dimerized AGA precursors into the N-terminal alpha- and the C-terminal beta-subunits takes place in the endoplasmic reticulum |
GO:0005783 AmiGO QuickGO |
654537 |
3.5.1.26 | extracellular |
- |
- |
209058 |
3.5.1.26 | extracellular |
high amounts of AGA-like protein is secreted in the venom, the venom AGA is secreted as fully activated enzyme |
- |
755152 |
3.5.1.26 | extracellular |
plasma |
- |
669745 |
3.5.1.26 | intracellular |
- |
GO:0005622 AmiGO QuickGO |
209054 |
3.5.1.26 | lysosome |
- |
GO:0005764 AmiGO QuickGO |
209047, 209048, 209051, 209052, 209055, 209061, 209066, 668879, 681417, 712162, 712919, 735290, 753573, 753910, 755339 |
3.5.1.26 | lysosome |
enzymic catalysis takes place in lysosomes |
GO:0005764 AmiGO QuickGO |
654537 |
3.5.1.26 | lysosome |
in the lysosomes, the C-termini of both alpha- and beta-subunits are trimmed by proteases, resulting in the mature form of AGA, though these trimming steps are not necessary for the catalytic activity of AGA |
GO:0005764 AmiGO QuickGO |
753910 |
3.5.1.26 | more |
Aurelia AGA possesses an N-terminal signal peptide |
- |
753910 |
3.5.1.26 | more |
L15R causes aspartylglucosaminuria and affects translocation of aspartylglucosaminidase |
- |
668879 |